Pyrazinamide

Question 14. a6: How safe is breast-feeding while taking anti-TB drugs? It is quite safe. In fact, most authorities believe that it is unnecessary to substitute formula feeding for breast milk in the light of the absence of reports of adverse effects among infants of nursing mothers and the relatively small doses that infants receive 52, 53, 56, ; . However, if both mother and infant are taking INH, the drug may reach supra-therapeutic doses in the nursing infant. In this circumstance, bottlefeeding is recommended. Supplemental pyridoxine should given to an infant who is taking INH or whose mother who is breast feeding ; is taking INH. Pyridoxine deficiency may cause seizures in the newborn 55, 56, 69 ; . b. Patients with liver disease or past history of liver disease Protocol applies to a patient with liver disease and who presents with signs and symptoms highly suggestive of PTB Question 14. b1: What treatment regimen should be initiated? Patients with hepatitis virus carriage or a past history of acute hepatitis or excessive alcohol consumption without clinical evidence of chronic liver disease These patients can receive the usual short course chemotherapy regimen 70 ; . ii. Patients with established chronic liver disease Isoniazid plus rifampicin plus one or two non-hepatotoxic drugs such as streptomycin and ethambutol can be used for a total treatment duration of 8 months 2SHRE 6HR ; . An alternative regimen is streptomycin plus isoniazid plus ethambutol in the initial phase followed by isoniazid and ethambutol in the continuation phase, with a total treatment duration of 12 months 2SHE 10HE ; . iii. Patients with hepatic failure It is recommended that streptomycin and ethambutol be given. If a third drug is needed, isoniazid or rifampicin can be given cautiously in lowered doses. iv. Patients with acute hepatitis unrelated to TB or anti-TB treatment In this case, clinical judgement is necessary. In some cases it is possible to defer TB treatment until the acute hepatitis has resolved. In other cases, when it is necessary to treat TB during acute hepatitis, the combination of streptomycin and ethambutol up to a maximum duration of 3 months is the safest option until the hepatitis has resolved. The patient can then receive a continuation phase of 6 months isoniazid and rifampicin 3SE 6HR ; . i. Precautions and monitoring Since liver injury is the major toxic effect of pyrazinamide, especially in higher doses, great caution should be observed in patients with pre-existing hepatic abnormalities 71 ; , and should not be given in patients with chronic liver disease. Liver function tests should be monitored closely in patients being given hepatotoxic drugs. Treatment regimens should be re-evaluated if there is: a. an increase in liver enzymes by 5x the normal value b. further deterioration in liver function in patients with hepatic failure 72 ; . c. Patients with renal insufficiency renal failure Protocol applies to patients with renal failure and who presents with signs and symptoms highly suggestive of TB. By Lorelie Heisinger, IPS Lobbyist The 2003 Session of the Iowa General Assembly convenes on Monday, January 13th. The session promises to be an interesting one, full of challenges and opportunities. In some ways, the 2003 legislature is similar to last year's. Republicans continue to maintain majority control of both the House and the Senate a 29-21 majority in the Senate, and a 56-44 majority in the House ; . The Governorship is still held by incumbent Tom Vilsack. However, 41 of the 150 legislators arriving in January are newcomers, who will have plenty of energy and new ideas to implement. Governor Vilsack has accepted the resignations of a number of key department heads, including the Department of Human Services and the Department of Corrections. New administrators in these positions will similarly arrive with new ideas and energy. The Iowa Psychiatric Society's legislative agenda for 2003 includes the passage of mental health parity legislation; passage of legislation to limit actions the state can take to restrict access to mental health drugs; and passage of legislation to ensure insurance coverage of off-label prescriptions. In addition, IPS will be responding to challenges presented by continuing budget difficulties and recommendations to close several mental health institutions. You can find information about legislation under consideration and how to contact your legislator at legis ate.ia . Or you can contact me at 319 ; 833-0649 or loreleilaw mchsi and seroquel, because rifampin. It is not possible to clinically distinguish pyrazinamide-induced hepatitis from hepatitis caused by isoniazid or rifampicin; test dosing is required this is discussed in detail in tuberculosis treatment ; other side effects include nausea and vomiting , anorexia , sideroblastic anemia , skin rash , urticaria , pruritus , hyperuricemia , dysuria , interstitial nephritis , malaise ; rarely porphyria , and fever. DESCRIPTION OF IMPRINT VERY IMPORTANT THAT MEDICATION IS TAKEN AS DIRECTED CONTROLLED SUBSTANCE, DANGEROUS UNLESS OTHER DI NOT TAKE ASPIRIN WITH OUT CONSENT OF PHYSICIAN OBTAIN MEDICAL A DVICE BEFORE TAKING NON-PRESCRIPTION DRUG USE AS GARGLE, NOT TO BE SWALLOWED SHAKE WELL BEFORE USING THIS BOTTLE IS NOT FULL, BUT CONTAINS EXACT AMOUNT PLEASE READ ENCLOSED PATIENT INFORMATION NO. , SEE OUTSIDE CONTAINER FOR DIRECTIONS CAUTION, FEDERAL LAW PROHIBITS TRANSFER OF DRUG . YOUR PHARMACIST CAN PROVIDE IMPORTANT INFORMATION CAUTION THIS DRUG CAN CAUSE DROWSINESS MAY CAUSE DROWSINESS OR DIZZINESS CAUTION, MAY CAUSE DROWSINESS OR DIZZINESS . DRUG MAY IMPAIR ABILITY TO DRIVE, USE CAUTION . SHAKE WELL & KEEP IN REFRIGERATOR, DISCARD . NOT REFRIGERATE, NOTE: RED PRINT NOT A CHILD PROOF CONTAINER; PATIENT'S REQUEST FEDERAL LAW REQUIRES THAT DISPENSE IN SAFETY CONTAINER NOT APPROVED FOR MEDICAID INCREASE IN COST DUE TO MFG. INCREASE MEDICAID WILL NOT REIMBURSE REFILLS EXPIRE 1 YEAR FROM ORIGINAL DATE ACC. TO LAW, PRESC. CANNOT BE REFILLED WITHIN 6 MONTHS THIS PRESCRIPTION MAY BE REFILLED 1 TIME THIS PRESCRIPTION MAY BE REFILLED 2 TIMES THIS PRESCRIPTION MAY BE REFILLED 3 TIMES THIS PRESCRIPTION MAY BE REFILLED 4 TIMES THIS PRESCRIPTION MAY BE REFILLED 5 TIMES THIS RX CAN ONLY BE REFILLED BY DOCTORS AUTHORIZATION , CALL . PHYSICIANS AUTHORIZATION REQUIRED FOR REFILL, CALL . AVOID WAITING FOR REFILLS, CALL AHEAD THIS PRESCRIPTION CAN BE REFILLED, PLEASE BRING CONTAINER . THIS PRESCRIPTION, REFILLED ON YOU MUST SEE PHYSICIAN BEFORE PRESCRIPTION CAN BE REFILLED CAUTION, FEDERAL LAW PROHIBITS DISPENSING WITHOUT PRESCRIPTION THANK YOU, WE APPRECIATE YOUR BUSINESS and quinine.

Division of Endocrinology and Metabolism Y.H., D.Y., I.M., M.K., J.K., M.S., K.N. ; , Department of Medicine, Kurume University School of Medicine, Fukuoka, 830 Japan; and Eye Division of Olympia Clinic Y.I. ; , 150 Tokyo, Japan and ropinirole. Arcalion home allergies anti-depressants anti-infectives anti-psychotics anti-smoking antibiotics asthma cancer cardio & blood cholesterol diabetes epilepsy gastrointestinal hair loss herpes hiv hormonal men's health muscle relaxers other pain relief parkinson's rheumatic skin care weight loss women's health allegra atarax benadryl clarinex claritin clemastine periactin phenergan pheniramine zyrtec anafranil celexa cymbalta desyrel effexor elavil, endep luvox moclobemide pamelor paxil prozac reboxetine remeron sinequan tofranil wellbutrin zoloft albenza amantadine aralen flagyl grisactin isoniazid myambutol py4azinamide sporanox tinidazole vermox abilify clozaril compazine flupenthixol geodon haldol lamictal lithobid loxitane mellaril risperdal seroquel zyprexa nicotine zyban achromycin augmentin bactrim biaxin ceclor cefepime ceftin chloromycetin cipro, ciloxan cleocin duricef floxin, ocuflox gatifloxacin ilosone keftab levaquin minomycin noroxin omnicef omnipen-n oxytetracycline rifater rulide suprax tegopen trimox vantin vibramycin zithromax advair aerolate, theo-24 brethine, bricanyl ketotifen metaproterenol proventil, ventolin serevent singulair arimidex casodex decadron eulexin femara levothroid, synthroid nolvadex provera, cycrin ultram vepesid zofran acenocoumarol aceon adalat, procardia altace atenolol amlodipine avapro caduet calan, isoptin capoten captopril hctz cardizem cardura catapres cilexetil, atacand clonidine, hctz combipres cordarone coreg coumadin cozaar dibenzyline diovan fosinopril hydrochlorothiazide hytrin hyzaar inderal ismo, imdur isordil, sorbitrate lanoxin lasix lercanidipine lopressor lotensin lozol micardis minipress moduretic normadate norpace norvasc plavix plendil prinivil, zestril prinzide rythmol tenoretic tenormin trental valsartan hctz vaseretic vasodilan vasotec zebeta crestor lipitor lopid mevacor pravachol tricor zocor accupril actos alpha-lipoic acid amaryl avandia diamicron mr gliclazide metformin glucophage glucotrol glucotrol xl glucovance lyrica micronase orinase prandin precose starlix depakote dilantin lamictal neurontin sodium valproate tegretol topamax trileptal valparin aciphex asacol bentyl cinnarizine colospa compazine cromolyn sodium cytotec imodium motilium nexium nexium fast pepcid ac pepcid complete prevacid prilosec propulsid protonix reglan stugil zantac zelnorm zofran propecia, proscar famvir rebetol valtrex zovirax combivir duovir-n epivir pyrazzinamide retrovir sustiva videx viramune zerit ziagen aldactone calciferol danocrine decadron prednisone provera, cycrin synthroid avodart cialis flomax hytrin levitra propecia, proscar viagra lioresal soma tizanidine ibuprofen zanaflex accupril alpha-lipoic acid amantadine aralen arcalion aricept ascorbic acid benadryl bentyl betahistine calciferol carbimazole compazine cyklokapron ddavp, stimate detrol dihydroergotoxine ditropan dramamine exelon florinef imitrex imuran isoniazid lasix melatonin myambutol nimotop orap persantine piracetam pletal quinine rifampin rifater rocaltrol strattera ticlid tiotropium urecholine urispas urso vermox zyloprim acetylsalicylic acid advil, medipren celebrex flunarizine imitrex ketorolac maxalt ponstel tylenol ultram benadryl ditropan eldepryl requip sinemet trivastal advil, medipren arava colchicine decadron feldene indocin sr mobic naprelan naprosyn zyloprim betamethasone differin nizoral oxsoralen prograf retin-a xenical advil, medipren allyloestrenol clomid, serophene diflucan evista folic acid fosamax isoflavone nexium parlodel ponstel prevacid prilosec progesterone provera, cycrin rocaltrol tibolone generic arcalion generic name: sulbutiamine ; qty. BNF : 5 . Ethambutol HCl Tab 100mg Ethambutol HCl Tab 400mg Total for chemical entity : Isoniazid Elix BPC 50mg 5ml S F Isoniazid Liq Spec 50mg 5ml Isoniazid Oral Soln 50mg 5ml S F Isoniazid Tab 100mg Isoniazid Tab 50mg Total for chemical entity : Pirilene Tab 500mg Pyrafat Tab 500mg Pyrazinam8de Liq Spec 500mg 5ml Zinamide Tab 500mg Total for chemical entity : Mycobutin Cap 150mg Total for chemical entity : Rifadin Cap 150mg Rifadin Cap 300mg Rifadin Syr 100mg 5ml Rifampicin Cap 150mg and tretinoin.
However, the mean peak plasma concentration of rifampin was approximately 18% lower following the single-dose administration of rifater tablets as compared to rifadin administered in combination with p6razinamide and isoniazid.
Specimen: serum ref. range: 35 U ml Mainly used for monitoring treatment and progress in established ovarian cancer. Values 65 are consistent with ovarian malignancy in a patient with an ovarian mass. Elevated levels may be found in other malignancies, or occasionally other nonmalignant conditions including endometriosis, PID pelvic inflammatory disease ; , cirrhosis, renal failure and pregnancy and retrovir and pyrazinamide, for example, prednisone.

JACC Vol. 47, No. 5, 2006 March 7, 2006: 108290 occurrence of severe congestive heart failure or requirement for intra-aortic balloon pump or cardiopulmonary resuscitation p 0.0081 ; . The main and novel findings of this report are: 1 ; RV involvement in TLVABS is common, transient, and, when present, portends a longer and more critical hospitalization course as compared with patients with isolated LV involvement; and 2 ; RV involvement, when present, follows a similar pattern of regional wall motion abnormalities as does LV involvement in this syndrome. It is now clear that RV function is one of the most useful indicators for patient survival in ischemic heart failure 2 ; and in patients with congenital heart disease 3 ; . In our study, we show for the first time that RV involvement was common in patients with TLVABS, with approximately one-third of patients presenting with detectable RV dysfunction on echocardiography. Even if we assume that all other five patients who did not have echocardiography at initial evaluation had normal RV function, at least one-quarter 8 of 30 ; of patients with TLVABS have RV involvement. The RV involvement was transient but had a significant impact on hospitalization length and hemodynamic instability. This effect was independent from the accompanying LV dysfunction. Clinicians should be aware of the possibility of RV dysfunction because it might have a significant impact on patient morbidity, management, and, ultimately, outcome. The major limitation of the study lies in its retrospective nature and relatively small number of patients. The echocardiograms were obtained for clinical use and specific imaging was not performed for the assessment of RV function. In addition, although echocardiography is used to assess RV function, technical limitations to imaging exist because of the complexity of the RV anatomy 4 ; . In conclusion, in TLVABS, RV involvement is relatively common and is reversible. Right ventricular involvement has a.
There's no reason for an older woman to take combination hormone therapy, concludes sally shumaker, a professor of public health at wake forest university school of medicine, winston-salem and the lead author of the dementia study and rifater. CONFERENCE PRESENTATIONS 1. Ekpebegh CO, Coetzee EJ, Levitt NS. Retrospective analysis of pregnancy outcome in type 2 diabetes: comparison of insulin and oral hypoglycaemic agent therapy at Groote Schuur Hospital from 1995 1997. 41st SEMDSA Congress, Johannesburg 9 12 April 2005. 2. Goedecke JH, Wake, DJ, Levitt NS, Lambert EV, Collins MR, Morton NM, Walker BR, Seckl JR. Insulin sensitivity and abdominal adipokine expression are not influenced by ethnicity in South African women. 41st SEMDSA Congress, Johannesburg 9 12 April 2005. 3. Heckmann J, Fredericks A, Evans A, Norman J, Blockman M, Lambson E, Owen E, Spearman W, Smith P. Ethical Issues in Designing Clinical Trials for Complementary and traditional Medicines Dr Marc Blockman SA Pharmacology Conference Cape Town 2005. 4. Levitt NS, Bradshaw D. The impact of HIV AIDS on diabetes prevalence and diabetes healthcare needs in South Africa Projections for 2010. 41st SEMDSA Congress, Johannesburg 9 12 April 2005. 5. McIlleron H, P Wash, A Burger, J Norman, PI Folb, P Smith. HIV-infection and rifampicin, isoniazid, pyrazinamide and ethambutol pharmacokinetcs in a cohort of South African tuberculosis patients. Proceedings of: 6th International Workshop on Clinical Pharmacology of HIV therapy. April 2005. Abstract 86. 6. Micklesfield LK, Levitt NS, Dhansay MA, Norris SA, van der Merwe L, Lambert EV. Maternal and early life influences on Calcaneal ultrasound parameters ad metacarpal morphometry in 7 9 year old children. 41st SEMDSA Congress, Johannesburg 9 12 April 2005. 7. Roberts, L., Hoppe, H., Wiehart, U., Meredith, S., Van Schalkwyk, D., Egan, J. and Weber, B. Understanding Plasmodium falciparum endocytosis: antimalarial drugs as tools. Keystone Symposium: Drugs against protozoan parasites: target selection, structural biology and medicinal chemistry. 2005 ; Colorado, USA. 8. Ross IL, Buchanan M, Sheppard MC, Eggo M. Activated TIE-2 expression is decreased in thyroid cancer. 41st SEMDSA Congress, Johannesburg 9 12 April 2005. 9. Wiehart, U, M. Rautenbach and H. Hoppe. Antimalarial properties of haemolytic antifungal compounds. Keystone Symposium: Drugs against protozoan parasites: target selection, structural biology and medicinal chemistry. 2005 ; Colorado, USA. Roles in the industry, creating lower-cost sources of help but also nurturing potential future rivals for the large pharmaceutical companies. Any planning effort must answer the question of how this trend toward outsourcing will affect the industry in future years. More tactically, the implications for profit streams must also be addressed. There is increasing consensus, and indeed evidence, that the transformations resulting from these trends will have significant impact during the careers of current senior executives. The acceleration of these factors was forecast as early as the 19992000 time frame in the original Pharma 2005 report, emphasizing the importance of finding new ways to predict and understand the future of this industry. MAPPING THE FUTURE: PHASE 1 The process for mapping the future begins by defining that future in high-level terms, so that management can next complete the secondary levels of information required to understand it and possibly respond to it in detail. Initially we define today's current trends and then create a vision for periods of time that extend far beyond normal comfort levels. In other words, we carry out standard scenario planning, but extend that exercise by at least 10 to 15 years. This approach is exactly the opposite of what is normally done. Usually, a manager goes from today's situation often called the as-is circumstance ; forward 2 or 3 years to the to-be situation. In effect, the future is then defined as one of two or three variations of a straightforward extension of the present. This is classic scenario planning. In contrast, by taking the approach described in this paper, we can begin factoring in disruptions that are not extensions of today's patterns, such as the introduction of as yet unknown classes of medications, or natural disasters, or the evolution of unknown diseases. By initially selecting a limited number of detailed research topics to explore regarding the future, we can make a great deal of sense of the resulting data and generate approaches that become the focus of future work streams. These results can be particular to a given industry such as those regarding the future evolution of stem cell research and its potential by-products ; or relevant to many indus.
Many states are strategizing to improve the cost-effectiveness of their Medicaid programs while maintaining the quality of care provided to Medicaid recipients. The below chart provides examples of initiatives that states have approved or implemented to contain Medicaid costs and mitigate budget shortfalls. Please note that this is not a comprehensive list of initiatives, but is only meant to provide an overview.1.

APPLICATION La BACTEC Pyrazinamde PZA ; Drug Kit trousse de pyrazinamide [PZA] BACTEC ; est conue pour le test de sensibilit la pyrazinamide. Cette trousse est destine principalement tre utilise avec le milieu BACTEC PZA Test Medium Milieu BACTEC pour test PZA ; , conjointement avec l'appareil BACTEC 460TB. La pyrazinamide est fournie sous forme lyophilise avec un fluide de reconstitution RF ; spcial utiliser avec le BACTEC PZA Test Medium afin de raliser le test de sensibilit du Mycobacterium tuberculosis. RESUME ET EXPLICATION Pour les tests conventionnels de sensibilit la pyrazinamide du M. tuberculosis, un milieu spcial pH 5, est requis.1 Pour le test de sensibilit BACTEC PZA, le BACTEC PZA Test Medium pH 6, 0 doit tre utilis.2 La PZA lyophilise et un fluide de reconstitution sont fournis pour faciliter la procdure BACTEC. Le produit doit tre rhydrat avec le fluide de reconstitution fourni avec la trousse. Le RF contient une substance qui stimule la croissance starate de polyoxythylne : POES ; . Lorsque la PZA reconstitue est ajoute au milieu, le POES est galement introduit dans le milieu. Le RF doit aussi tre ajout au BACTEC 12B Medium utilis pour raliser la culture avant le test. Le RF est galement ajout au flacon de contrle PZA Test Medium. PRINCIPES DE LA METHODE Pour raliser le test de sensibilit BACTEC PZA, le BACTEC PZA Test Medium pH 6, 0 doit tre utilis.2 A ce pH, l'activit de la PZA contre les mycobactries peut tre dtermine sans inhiber la croissance de la plupart des isolats de M. tuberculosis. Pour compenser l'augmentation du pH, une concentration plus leve de PZA 100 g mL ; est utilise dans le test BACTEC que dans le test conventionnel 25 50 g principe de la mthode du test de sensibilit BACTEC PZA est le mme que celui du test de sensibilit BACTEC des produits antituberculeux.3-5 Une fois la PZA reconstitue avec 5 mL de fluide de reconstitution, la concentration souhaite de PZA dans le PZA Test Medium est obtenue par addition de 0, 1 mL solution de rserve du produit au PZA Test Medium. REACTIFS Agent lyophilis Pyrazinakide . 000 g flacon Fluide de reconstitution RF ; Starate de polyoxythylne . 000 g mL Eau traite . Avertissements et prcautions : Rserv au diagnostic in vitro. Ce produit contient du caoutchouc naturel sec. Des microorganismes pathognes, notamment les virus de l'hpatite et de l'immunodficience humaine, sont susceptibles d'tre prsents dans les chantillons cliniques. Respecter les Prcautions standard 6-9 et les consignes en vigueur dans l'tablissement pour manipuler tout objet contamin avec du sang ou d'autres liquides organiques. Le matriel contamin doit tre strilis par traitement l'autoclave avant limination. Reconstituer le flacon de produit uniquement avec le fluide de reconstitution se rfrer la notice d'emploi PP-071JAA du BACTEC PZA Test Medium ; . Conservation et stabilit Avant reconstitution, la PZA Drug Kit doit tre stocke une temprature comprise entre 2 et 8 Une fois reconstitu, le produit peut tre congel en petites aliquotes une temprature comprise entre -5 et -70 C jusqu' six mois. Eviter les cycles rpts de conglation-dconglation. La date de premption s'applique la bouteille non ouverte de produit lyophilis stocke selon les recommandations. Elimination Tous les flacons usags doivent tre striliss par traitement l'autoclave avant limination. PREPARATION DES ECHANTILLONS Se rfrer la notice d'emploi du BACTEC PZA Test Medium PP-071JAA. Gastric lavage as soon as possible within the first 2 to 3 hours after ingestion is advised, but it should not be attempted until convulsions are under control. To treat convulsions, administer I.V. diazepam or short-acting barbiturates, and I.V. pyridoxine usually 1 mg l mg isoniazid ingested ; . Following evacuation of gastric contents, the instillation of activated charcoal slurry into the stomach may help absorb any remaining drug from the gastrointestinal tract. Antiemetic medication may be required to control severe nausea and vomiting. RAPID CONTROL OF METABOLIC ACIDOSIS IS FUNDAMENTAL TO MANAGEMENT. Give I.V. sodium bicarbonate at once and repeat as needed, adjusting subsequent dosage on the basis of laboratory findings eg, serum sodium, pH, etc ; . Forced osmotic diuresis must be started early and should be continued for some hours after clinical improvement to hasten renal clearance of drug and help prevent relapse; monitor fluid intake and output. Hemodialysis is advised for severe cases; if this is not available, peritoneal dialysis can be used along with forced diuresis. Along with measures based on initial and repeated determination of blood gases and other laboratory tests as needed, utilize meticulous respiratory and other intensive care to protect against hypoxia, hypotension, aspiration pneumonitis, etc. DOSAGE AND ADMINISTRATION Adults: Patients should be given the following single daily dose either 1 hour before or two hours after a meal with a full glass of water: - Patients weighing 44 kg or less : 4 tablets - Patients weighing between 45-54 kg: 5 tablets - Patients weighing 55 kg or greater: 6 tablets RIFATER rifampin isoniazid pyrazinamide ; is recommended in the initial phase of short-course therapy which is usually continued for 2 months. When indicated, the addition of other antituberculosis drugs, such as streptomycin and or ethambutol, should be considered. Following the initial phase, treatment should be continued with rifampin and isoniazid for at least 4 months. Treatment should be continued for longer if the patient is still sputum or culture positive, if resistant organisms are present, or if the patient is HIV positive. Concomitant administration of pyridoxine B ; is recommended in the malnourished, in those predisposed to neuropathy eg, alcoholics and diabetics ; , and in adolescents. Invasive, and more comfortable would always be welcome. -- Susan Braun, Susan G. Komen Breast Cancer Foundation A number of breast cancer groups also said the limitations of mammogram technology can lead to unnecessary biopsies and missed cases of breast cancer. "We tend to overdiagnose or overtreat women because it is just not very specific, " said National Breast Cancer Coalition Vice President Carolina Hinestrosa, who was diagnosed with the disease in 1996. "Clearly we could do better." "Any test that is easier, more available, less invasive, and more comfortable would always be welcome, " said Susan Braun, president and CEO of the Susan G. Komen Breast Cancer Foundation. But until new methods are perfected, women should check their breasts themselves each month and continue to get annual mammograms. "It is certainly the best available screening tool, " Braun said.

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